• ## Exponential Growth of NCBI Genomes

I have been studying bioinformatics for 4 years and had the privilege to work in a sequencing lab and personally see the technology change and accelerate. When I started work at the CGB in 2010, a whole genome cost around $10,000 to sequence on an Illumina GA II machine. In 2013, the IU Bioinformatics Club resequenced a human genome for$4,000. Now Google’s Calico is pushing for the \$1,000 human genome. This price point make whole genome resequencing more affordable than the average trip to the hospital, making personalized medicine very attractive.

31 Mar 2014

• ## Recomb 2014

I will be presenting a poster at http://www.compbio.cmu.edu/recomb/ this year.

20 Feb 2014

• ## Genome Browsers

For the past few years, I’ve used IGB as my preferred coverage viewer. I appreciated that it was an open-source project, and I could recommend colleagues to use it since it was an open-source project and it was easy enough to launch a java program on any system. Recently, I switched to IGV since the auto-scaling and data transformation features in IGB were not functioning on bedgraph data. As highlighted by the red circles in the figure, low values are hidden in IGB since the y-axis of the data track does not rescale based upon the viewing window.